Mapping the gap: scoping review protocol on medication safety and adverse reactions in dental practice

Authors

  • Inês Lopes Cardoso University Fernando Pessoa
  • Madalena Silva
  • Beatriz Loibl
  • Maria Teresa Moreira
  • Maria Inês Guimarães

DOI:

https://doi.org/10.62741/ahrj.v3iSuppl.142

Keywords:

dentistry, adverse drug reactions, pharmacovigilance, prevalence, dental treatment

Abstract

Introduction: Adverse drug reactions are a relevant yet frequently underreported concern in dental practice, particularly regarding their prevalence and association with commonly prescribed medications such as antibiotics, analgesics, and anti-inflammatory drugs.
Objectives: The aim is to systematically map adverse drug reactions in dental practice, identifying implicated drugs, reported reactions, and current reporting practices.
Methodology: A scoping review will be conducted in accordance with the Joanna Briggs Institute methodology. Scientific databases and grey literature will be searched using the following keywords: adverse drug reactions, pharmacovigilance, dentistry, prevalence, and dental treatment.
Results: This scoping review will include studies aligned with the defined objective, aiming to map the existing evidence on the prevalence of adverse drug reactions in dental practice and the medications most commonly associated with them. This study will synthesize global evidence on adverse drug reactions in dental practice, will highlight underreporting, gaps in awareness and
training, and regional variability, and will propose educational, curricular, digital, and interdisciplinary strategies to strengthen pharmacovigilance, improve prescribing safety, and enhance patient safety in dentistry.
Conclusion: The findings of this scoping review will support safer prescribing practices in dentistry and contribute to a better understanding of pharmacovigilance within dental care settings.

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Published

25-05-2026