Factors influencing nurses’ adherence to ventilator-associated pneumonia prevention bundles: a scoping review
DOI:
https://doi.org/10.62741/ahrj.v3i2.148Keywords:
Critical care nursing, Patient Care Bundles, Guideline adherence, Pneumonia Ventilator-Associated, Disease preventionAbstract
Introduction: Ventilator-associated pneumonia is a healthcare-associated infection with a significant impact on morbidity, mortality, length of stay, and hospital costs in intensive care units. Nurses’ adherence to prevention bundles plays a key role in the effectiveness of these interventions, although it is influenced by multiple factors.
Objective: To map the available scientific evidence on the factors influencing nurses’ adherence to ventilator-associated pneumonia prevention bundles in intensive care units.
Methodology: Scoping review conducted in accordance with the Joanna Briggs Institute methodology and PRISMA-ScR. Eligibility criteria were defined according to the PCC framework (Participants – nurses providing care to patients undergoing mechanical ventilation in the ICU; Concept – studies addressing nurses’ adherence or non-adherence to ventilator-associated pneumonia prevention bundles, as well as factors associated with their implementation; Context – studies conducted in intensive care units or equivalent hospital settings providing care to critically ill patients receiving invasive mechanical ventilation). Studies published in Portuguese, English, and Spanish were included, identified through the MEDLINE Complete (via PubMed), CINAHL Complete, MedicLatina, and Cochrane Central Register of Controlled Trials (via EBSCOhost) databases, and selected by two independent reviewers, with a third reviewer involved in cases of disagreement. The search was conducted in March 2026.
Results: Five core categories were identified: team training and capacity building; implementation strategies and practice monitoring; institutional resources and organizational conditions; professional and organizational factors; and clinical outcomes and care indicators. Continuous training, audit and feedback, practice monitoring, availability of resources, and institutional support were found to promote adherence, whereas workload, staff turnover, communication failures, and resource shortages may hinder it.
Conclusion: Nurses’ adherence to ventilator-associated pneumonia prevention bundles is influenced by multiple and interdependent factors, reinforcing the importance of integrated strategies involving training, monitoring, and organizational support to promote safe, evidence-based practice.
References
Alanazi S, Alonazi WB. Enhancing critical care practitio-ner’s knowledge and adherence to ventilator-associated events bundle: a comprehensive analysis. Front Med (Lausanne). 2024;11. https://doi.org/10.3389/fmed.2024.1365742
Centers for Disease Control and Prevention. Ventilator-associated pneumonia basics. Updated May 16, 2024. Accessed May 22, 2025. https://www.cdc.gov/ventilator-associated-pneumonia/about/
Branco A, Lourençone EMS, Monteiro AB, Fonseca JP, Blatt CR, Caregnato RCA. Education to prevent ventilator-associated pneumonia in intensive care unit. Rev Bras Enferm. 2020;73(6):e20190477. https://doi.org/10.1590/0034-7167-2019-0477
Martinez-Reviejo R, Tejada S, Jansson M, Ruiz-Spinelli A, Ramirez-Estrada S, Ege D, et al. Prevention of ventilator-associated pneumonia through care bundles: a systematic re-view and meta-analysis. J Intensive Med. 2023;3(4). https://doi.org/10.1016/j.jointm.2023.04.004
Al-Harthi F, Al-Noumani H, Matua GA, Al-Abri H, Joseph A. Nurses’ compliance to ventilator-associated pneumonia pre-vention bundle and its effect on patient outcomes in intensive care units. Nurs Crit Care. 2025;30(3). https://doi.org/10.1111/nicc.70043
Mastrogianni M, Katsoulas T, Galanis P, Korompeli A, Myri-anthefs P. The impact of care bundles on ventilator-associated pneumonia (VAP) prevention in adult ICUs: a systematic re-view. Antibiotics (Basel). 2023;12(2):227. https://doi.org/10.3390/antibiotics12020227
Campos A, Montebello J, Silva G, Júnior H. Conhecimento e adesão às medidas preventivas da pneumonia associada à ven-tilação mecânica de COVID-19. Rev Epidemiol Control Infect. 2024;14(4). https://doi.org/10.17058/reci.v14i4.19180
Silva SG, Nascimento ERP, Salles RK. Bundle de prevenção da pneumonia associada à ventilação mecânica: uma construção coletiva. Texto Contexto Enferm. 2012;21(4):837-844. https://doi.org/10.1590/S0104-07072012000400014
Mota PT, Barilli SLS, Treviso P, Santos AAS. Atuação de técni-cos de enfermagem na prevenção de pneumonia associada à ventilação mecânica: estudo qualitativo. Rev Baiana Enferm. 2023;37:e47614. https://doi.org/10.18471/rbe.v37.47614
Oliveira EK, Silva JL, Amâncio NFG, Reis JRG. Bundle para prevenção de pneumonia associada à ventilação mecânica: re-visão de literatura. Rev JRG Estud Acad. 2025;18:e181704. https://doi.org/10.55892/jrg.v8i18.1704
Giang BTH, Matsubara C, Okamoto T, Hoan HM, Yonehiro Y, Nguyen DT, et al. The development of a 10-item ventilator-associated pneumonia care bundle in the general intensive care unit of a tertiary hospital in Vietnam: lessons learned. He-althcare (Basel). 2023;13(5):443. https://doi.org/10.3390/healthcare13050443
Portugal. Ministério da Saúde. Despacho nº 9390/2021, de 24 de setembro. Diário da República. 2021;2(187):96-103. https://www.dgs.pt
Peters MDJ, Marnie C, Tricco AC, Pollock D, Munn Z, Alexan-der L, et al. Updated methodological guidance for the conduct of scoping reviews. JBI Evid Synth. 2020;18(10):2119-2126. https://doi.org/10.11124/JBIES-20-00167
Pollock D, Peters MDJ, Khalil H, McInerney P, Alexander L, Tricco AC, et al. Recommendations for the extraction, analysis, and presentation of results in scoping reviews. JBI Evid Synth. 2023;21(3):520-532. https://doi.org/10.11124/JBIES-22-00123
Bardin L. Análise de conteúdo. Edições 70; 2016.
Mogyoródi B, Skultéti D, Mezőcsáti M, Dunai E, Magyar P, Hermann C, Gál J, Hauser B, Iványi ZD. Effect of an educatio-nal intervention on compliance with care bundle items to pre-vent ventilator-associated pneumonia. Intensive Crit Care Nurs. 2023;75:103342. https://doi.org/10.1016/j.iccn.2022.103342
Abad CL, Formalejo CP, Mantaring DML. Assessment of knowledge and implementation practices of the ventilator ac-quired pneumonia (VAP) bundle in the intensive care unit of a private hospital. Antimicrob Resist Infect Control. 2021;10:161. https://doi.org/10.1186/s13756-021-01027-1
Page MJ, McKenzie JE, Bossuyt PM, Boutron I, Hoffmann TC, Mulrow CD, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. MetaArXiv Pre-print. 2020. https://doi.org/10.31222/osf.io/v7gm2
Weston Smith N, Spivey M. Promoting subglottic secretion drainage: a quality improvement project in a UK critical care unit. BMJ Open Qual. 2021;10:e001269. https://doi.org/10.1136/bmjoq-2020-001269
Debas SA, Zeleke ME, Mersha AT, Melesse DY, Admassie BM, Workie MM, Chekol WB, Admass BA. Evaluation of ventilator-associated pneumonia care practice in the intensive care units of a comprehensive specialized hospital in Northwest Ethiopia: a 1.5-year prospective observational study. BMC Anesthesiol. 2024;24:361. https://doi.org/10.1186/s12871-024-02753-w
Akdogan O, Ersoy Y, Kuzucu Ç, Gedik E, Togal T, Yetkin F. Assessment of the effectiveness of a ventilator associated pneumonia prevention bundle that contains endotracheal tube with subglottic drainage and cuff pressure monitorization. Braz J Infect Dis. 2017;21(3):276-281. https://doi.org/10.1016/j.bjid.2017.01.002
Buterakos R, Jenkins PM, Cranford J, Haake RS, Maxson M, Moon J, Rice B, Sachwani-Daswani GR. An in-depth look at ventilator-associated pneumonia in trauma patients and efforts to increase bundle compliance, education and documentation in a surgical trauma critical care unit. Am J Infect Control. 2022;50(12):1333-1338. https://doi.org/10.1016/j.ajic.2022.01.029
Tricco AC, Lillie E, Zarin W, O’Brien KK, Colquhoun H, Levac D, et al. PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation. Ann Intern Med. 2018;169(7):467-473. https://doi.org/10.7326/M18-0850
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Athena Health & Research Journal

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright of published papers is assigned to the Journal, but all content is licensed under the terms of Creative Commons Non-comercial 4.0 International License. Thus users are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.








